Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.78 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651297 | 0.88 | AR (1.00) | AR | |
| SCHEMBL13651237 | 0.84 | AR (0.74) | AR | |
| SCHEMBL13651219 | 0.83 | AR (0.73) | AR | |
| SCHEMBL13651294 | 0.83 | AR (0.73) | AR | |
| SCHEMBL13651222 | 0.83 | AR (0.73) | AR | |
| SCHEMBL13651265 | 0.83 | AR (0.64) | AR | |
| SCHEMBL13651306 | 0.82 | AR (0.63) | AR | |
| SCHEMBL13651339 | 0.81 | AR (0.75) | AR | |
| SCHEMBL13651254 | 0.81 | AR (0.69) | AR | |
| SCHEMBL13651249 | 0.80 | AR (0.82) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131196-A1 | SUBSTITUTED PYRROLIDINE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-29 | — | — | WO | disclosed |