SCHEMBL13651297

SCHEMBL13651297

C[C@@H]1N(c2ccc(C#N)c(Cl)c2)CC[C@@]1(O)c1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13651296 0.91 AR (0.84) AR
SCHEMBL13651276 0.88 AR (0.78) AR
SCHEMBL13651221 0.84 AR (1.00) AR
SCHEMBL13651237 0.83 AR (0.74) AR
SCHEMBL13651219 0.83 AR (0.73) AR
SCHEMBL13651294 0.83 AR (0.73) AR
SCHEMBL13651222 0.83 AR (0.73) AR
SCHEMBL13651342 0.82 AR (0.70) AR
SCHEMBL2392581 0.81 AR (1.00) AR
SCHEMBL13651339 0.80 AR (0.75) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009131196-A1 SUBSTITUTED PYRROLIDINE DERIVATIVE AND USE THEREOF 武田薬品工業株式会社 (JP) 2009-10-29 WO disclosed