Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651300 | 0.82 | AR (0.54) | AR | |
| SCHEMBL13651229 | 0.82 | AR (0.56) | AR | |
| SCHEMBL13651250 | 0.82 | AR (0.56) | AR | |
| SCHEMBL13651227 | 0.79 | AR (0.53) | AR | |
| SCHEMBL13651289 | 0.76 | AR (0.50) | ARCHRM4 | |
| SCHEMBL17893756 | 0.76 | AR (0.49) | ARCHRM4MEN1KMT2AALDH1A1 | |
| SCHEMBL2388777 | 0.73 | AR (0.70) | AR | |
| SCHEMBL3339683 | 0.72 | AR (0.55) | ARCHRM4NR3C2 | |
| SCHEMBL1642826 | 0.71 | AR (0.50) | AR | |
| SCHEMBL2390086 | 0.71 | AR (0.47) | ARKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131196-A1 | SUBSTITUTED PYRROLIDINE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-29 | — | — | WO | disclosed |