Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.68 |
| ▸ | CDC25A | P30304 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12930306 | 0.83 | TRPA1 (0.74) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL1061089 | 0.81 | TRPA1 (1.00) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL1061091 | 0.81 | TRPA1 (1.00) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL12930285 | 0.81 | TRPA1 (0.69) | TRPA1CDC25A | |
| SCHEMBL1061471 | 0.80 | TRPA1 (0.72) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL1061470 | 0.80 | TRPA1 (0.72) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL12930177 | 0.74 | TRPA1 (0.61) | TRPA1CDC25A | |
| SCHEMBL29033840 | 0.73 | TRPA1 (0.66) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL29033842 | 0.73 | TRPA1 (0.66) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL12930348 | 0.72 | TRPA1 (0.61) | TRPA1CDC25AALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123080-A1 | INDOLINONE COMPOUND | アステラス製薬株式会社 (JP) | 2009-10-08 | — | — | WO | disclosed |