Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185804 | 0.87 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL13653136 | 0.87 | CA12 (0.45) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL4183406 | 0.86 | KMT2A (0.44) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL13653133 | 0.85 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL13653102 | 0.84 | MEN1 (0.42) | MEN1KMT2ARXFP1HDAC1RAB9A | |
| SCHEMBL27688295 | 0.83 | POLB (0.40) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL13653146 | 0.82 | MAPT (0.52) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL13653096 | 0.82 | MEN1 (0.43) | MEN1KMT2AHDAC1RAB9APOLB | |
| SCHEMBL13653122 | 0.81 | GCGR (0.37) | MEN1KMT2ARXFP1HDAC1PRMT5 | |
| SCHEMBL4184834 | 0.81 | GCGR (0.39) | MEN1KMT2ARXFP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
| CN-101080389-A | Indane amides with antiproliferative activity | BAYER PHARMACEUTICALS CORP (US) | 2007-11-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247590-A1 | Indane amides | MKI67, PPIP5K2, CCNA1 | PDE4A 2342/4885PDE4B 2871/4885PDE4C 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.