PPIP5K2

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 · O43314 · PPIP5K2 on Sugi Atlas →

7 patent compounds predicted against PPIP5K2, 5 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL3073446 SCHEMBL3073446 0.42 1/20
SCHEMBL3086364 SCHEMBL3086364 0.42 1/20
Phytic Acid Phytic Acid (SCHEMBL9463845) 0.41 1/20
SCHEMBL3206364 SCHEMBL3206364 0.40 1/20
Phytic Acid Phytic Acid (SCHEMBL5357994) 0.40 1/20

Clinical trials — most relevant to PPIP5K2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway PHASE4COMPLETED
Efficacy of Lithium Against Chemotherapy Induced Neutropenia in Breast Cancer Patients PHASE3COMPLETED
Pamidronate to Treat Osteogenesis Imperfecta in Children PHASE3COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP) PHASE2WITHDRAWN
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma PHASE1/PHASE2RECRUITING
Biological Effects of Quercetin in COPD Phase II PHASE2UNKNOWN
Biological Effects of Quercetin in COPD PHASE1/PHASE2UNKNOWN
Analysis of Tissues From Patients in Trial of Myo-Inositol to Prevent Lung Cancer PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer EARLY_PHASE1COMPLETED
Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) nanCOMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia nanRECRUITING
Tissue-nonspecific Alkaline Phosphatase in Phosphate and Pyrophosphate Homeostasis. nanCOMPLETED
Exome Sequencing for Atypical Femoral Fractures nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Studying Phosphorus Metabolism nanCOMPLETED
Vulvodynia: Identification of Potential Relevant Biomarkers nanCOMPLETED
Duality of Lipids: the Athlete's Paradox nanCOMPLETED
99Tc-MDP in Postmenopausal Women With Differentiated Thyroid Cancer and Osteoporosis nanCOMPLETED
Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism nanUNKNOWN
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia nanUNKNOWN
Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome nanCOMPLETED
The Study Aims to Investigate the Effects of Oral Inositols on Insulin-resistance in Children With Obesity. nanUNKNOWN
Plaque Calcium Characterization and Ruptured Plaques nanUNKNOWN
Hypophosphatemic Rickets in Norway nanUNKNOWN
TSH Receptor Mutations Among a Consanguineous Community nanCOMPLETED
Myoinositol Effect on Asprosin Levels nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PPIP5K2 binder may also engage these)

ProteinNameSimilarity
Q5XHF8 1.000 Q5XHF8 →
Q6ZQB6 1.000 Q6ZQB6 →
F4J8C6 1.000 F4J8C6 →
Q84WW3 1.000 Q84WW3 →
Q9VR59 1.000 Q9VR59 →
Q5REW0 1.000 Q5REW0 →
Q6PFW1 0.998 Q6PFW1 →
A7Z050 0.997 A7Z050 →
O74429 0.997 O74429 →
Q5RDF1 0.996 Q5RDF1 →
A2ARP1 0.994 A2ARP1 →
P91309 0.991 P91309 →
P0C644 0.990 P0C644 →
KAT8 Histone acetyltransferase KAT8 0.990 landscape →
Q5SNQ7 0.989 Q5SNQ7 →
Q8MJ26 0.989 Q8MJ26 →
P10759 0.989 P10759 →
KDM5B Lysine-specific demethylase 5B 0.989 landscape →
B4NBB0 0.989 B4NBB0 →
O09178 0.989 O09178 →
O08739 0.988 O08739 →
Q7Z401 0.988 Q7Z401 →
Q8WUF8 0.988 Q8WUF8 →
O01991 0.988 O01991 →
Q06685 0.988 Q06685 →
P43125 0.988 P43125 →
Q2KI89 0.988 Q2KI89 →
Q9Z1E4 0.988 Q9Z1E4 →
Q9STV0 0.988 Q9STV0 →
GYS2 Glycogen [starch] synthase, liver 0.987 landscape →