Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653201 | 0.93 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL13653241 | 0.92 | HDAC2 (0.47) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890545 | 0.91 | HDAC1 (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL13653246 | 0.91 | HDAC1 (0.53) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890537 | 0.88 | KDM1A (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890690 | 0.88 | KDM1A (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890584 | 0.88 | KDM1A (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890728 | 0.88 | KDM1A (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890534 | 0.88 | KDM1A (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 | |
| SCHEMBL24890539 | 0.88 | KDM1A (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247590-A1 | Indane amides | MKI67, PPIP5K2, CCNA1 | HDAC1 579/4885HDAC2 641/4885HDAC3 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.