Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622711 | 0.62 | MCHR1 (0.41) | KDM5B | |
| SCHEMBL13914940 | 0.61 | GSK3B (0.71) | GSK3B | |
| SCHEMBL13914942 | 0.61 | GSK3B (0.71) | GSK3B | |
| SCHEMBL18931746 | 0.59 | MAPT (0.50) | KDM5BPSDMEN1KMT2ANPC1 | |
| SCHEMBL2851684 | 0.57 | GSK3B (0.58) | GSK3B | |
| SCHEMBL13914960 | 0.57 | GSK3B (0.96) | GSK3B | |
| SCHEMBL13914910 | 0.56 | GSK3B (0.74) | GSK3B | |
| SCHEMBL4565591 | 0.56 | KCNH2 (0.41) | KDM5B | |
| SCHEMBL1651051 | 0.56 | GSK3B (1.00) | GSK3B | |
| SCHEMBL8342255 | 0.56 | GSK3B (0.72) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |