Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622946 | 0.75 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL25424302 | 0.74 | SCD (0.46) | KCNH2SCD | |
| SCHEMBL31434262 | 0.74 | SCD (0.46) | KCNH2SCD | |
| SCHEMBL13622864 | 0.73 | MCHR1 (0.58) | MCHR1KCNH2 | |
| SCHEMBL4237052 | 0.71 | MCHR1 (0.38) | MCHR1KCNH2KDM5B | |
| SCHEMBL4374344 | 0.67 | MCHR1 (0.39) | MCHR1 | |
| SCHEMBL31434274 | 0.65 | MAPT (0.41) | SCD | |
| SCHEMBL25766738 | 0.65 | MAPT (0.41) | SCD | |
| SCHEMBL13622943 | 0.65 | MCHR1 (0.51) | MCHR1 | |
| SCHEMBL31434301 | 0.64 | HTR2A (0.45) | KCNH2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137270-A2 | AZETIDINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-11-12 | — | — | WO | disclosed |