Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653995 | 0.92 | S1PR5 (0.38) | S1PR5FFAR4S1PR1PDCD1CD274 | |
| SCHEMBL12821314 | 0.90 | FFAR4 (0.38) | FFAR4NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13586221 | 0.90 | FFAR4 (0.38) | FFAR4NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12907934 | 0.87 | RARB (0.37) | NPC1RAB9ASMN1; SMN2BRD4ALOX5 | |
| SCHEMBL12822533 | 0.86 | FFAR4 (0.39) | S1PR5FFAR4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12717209 | 0.86 | FFAR4 (0.37) | FFAR4NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12994390 | 0.85 | FFAR1 (0.41) | SMN1; SMN2FFAR1MEN1KMT2A | |
| SCHEMBL12908502 | 0.84 | FFAR4 (0.38) | S1PR5FFAR4NPC1RAB9AS1PR1 | |
| SCHEMBL13654000 | 0.84 | PDE4D (0.36) | S1PR5FFAR4S1PR1S1PR4S1PR3 | |
| SCHEMBL12823856 | 0.84 | FEN1 (0.35) | FFAR4NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |