Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586363 | 0.92 | PDE4A (0.34) | PDE4DPDE4APDE4BPDE4CFFAR4 | |
| SCHEMBL12717309 | 0.92 | PDE4A (0.34) | PDE4DPDE4APDE4BPDE4CFFAR4 | |
| SCHEMBL12907040 | 0.89 | MRGPRX4 (0.38) | S1PR5FFAR1MRGPRX4FFAR4S1PR1 | |
| SCHEMBL12822535 | 0.88 | S1PR5 (0.35) | PDE4DPDE4APDE4BPDE4CS1PR5 | |
| SCHEMBL12822790 | 0.88 | PDE4A (0.33) | PDE4DPDE4APDE4BPDE4CS1PR5 | |
| SCHEMBL12907051 | 0.85 | FPR2 (0.32) | FFAR4FPR2 | |
| SCHEMBL10303179 | 0.85 | FFAR1 (0.40) | PDE4DPDE4APDE4BPDE4CS1PR5 | |
| SCHEMBL13586473 | 0.84 | FFAR1 (0.38) | FFAR1F10 | |
| SCHEMBL10303195 | 0.84 | FFAR1 (0.39) | PDE4DPDE4APDE4BPDE4CS1PR5 | |
| SCHEMBL13654004 | 0.84 | S1PR5 (0.36) | S1PR5FFAR1FFAR4S1PR1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |