Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586105 | 0.91 | FFAR1 (0.42) | MRGPRX4FFAR1CYP2C19 | |
| SCHEMBL10302255 | 0.89 | RXRG (0.41) | MRGPRX4LMNAHTTABCB1FFAR1 | |
| SCHEMBL12716908 | 0.88 | ABCB1 (0.41) | MRGPRX4LMNAHTTABCB1MAPT | |
| SCHEMBL10303125 | 0.88 | FFAR4 (0.37) | MRGPRX4LMNAHTTABCB1MAPK1 | |
| SCHEMBL12736578 | 0.88 | FFAR4 (0.44) | MRGPRX4LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10303116 | 0.85 | MAPT (0.43) | MRGPRX4LMNAHTTMAPK1HPGD | |
| SCHEMBL13654171 | 0.85 | GYS1 (0.39) | ABCB1MAPK1ALDH1A1FFAR1MAPT | |
| SCHEMBL10303075 | 0.85 | FFAR1 (0.47) | MRGPRX4MAPK1FFAR1MAPTERN1 | |
| SCHEMBL13586508 | 0.84 | FFAR1 (0.47) | LMNAHTTFFAR1 | |
| SCHEMBL13654114 | 0.84 | ABCB1 (0.39) | MRGPRX4ABCB1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |