Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.70 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.58 |
| ▸ | MTOR | P42345 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115582 | 0.86 | PIK3CD (0.70) | PIK3CDPIK3CAMTOR | |
| SCHEMBL28800823 | 0.86 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL29807776 | 0.86 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL3763296 | 0.85 | PIK3CD (0.82) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL5799334 | 0.85 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL13983406 | 0.84 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL3662525 | 0.83 | PIK3CD (0.80) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL3770642 | 0.83 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL13983063 | 0.82 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL731743 | 0.82 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123986-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | WO | disclosed |