Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775766 | 1.00 | BCHE (0.51) | BCHEPIK3CDDPP4HTTPKM | |
| SCHEMBL20284509 | 1.00 | BCHE (0.51) | BCHEPIK3CDDPP4HTTPKM | |
| SCHEMBL15976590 | 0.89 | BCHE (0.43) | BCHEPIK3CDDPP4SMN1; SMN2NOTUM | |
| SCHEMBL12225627 | 0.79 | BCHE (0.56) | BCHEPIK3CDDPP4HTTSMN1; SMN2 | |
| SCHEMBL10202194 | 0.79 | BCHE (0.56) | BCHEPIK3CDDPP4HTTSMN1; SMN2 | |
| SCHEMBL12225623 | 0.79 | BCHE (0.56) | BCHEPIK3CDDPP4HTTSMN1; SMN2 | |
| SCHEMBL20284248 | 0.79 | CCR5 (0.43) | BCHEDPP4ALDH1A1 | |
| SCHEMBL29089976 | 0.79 | BCHE (0.49) | BCHEDPP4ALDH1A1MAPK1 | |
| SCHEMBL20887598 | 0.77 | KDM4E (0.42) | BCHEHTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL15321741 | 0.76 | BCHE (0.50) | BCHEDPP4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019068613-A1 | NEW [1,6]NAPHTHYRIDINE COMPOUNDS AND DERIVATIVES AS CDK8/CDK19 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-04-11 | — | — | WO | disclosed |
| WO-2009123986-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | WO | disclosed |