⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189703 | 0.74 | HDAC3 (0.45) | — | |
| SCHEMBL22363448 | 0.71 | — | — | |
| SCHEMBL13667838 | 0.71 | — | — | |
| SCHEMBL2945836 | 0.71 | — | — | |
| SCHEMBL13623245 | 0.69 | KAT2B (0.34) | — | |
| SCHEMBL13437571 | 0.69 | TRPA1 (0.43) | — | |
| SCHEMBL15233019 | 0.69 | HDAC1 (0.41) | — | |
| Benzene SCHEMBL27800821 | 0.69 | TRPA1 (0.43) | — | |
| SCHEMBL22504876 | 0.69 | TRPA1 (0.43) | — | |
| SCHEMBL15590854 | 0.69 | HDAC3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384752-A | A method of preparing 3- azido-methyl furan compound | 中国科学院大连化学物理研究所 | 2019-02-26 | — | — | CN | claimed |
| CN-110997663-A | Benzofuran ureas or carbamates and heteroaromatic analogs thereof for use in therapy | 欧洲分子生物学实验室 | 2020-04-10 | — | — | CN | disclosed |
| CN-109384752-A | A method of preparing 3- azido-methyl furan compound | 中国科学院大连化学物理研究所 | 2019-02-26 | — | — | CN | disclosed |
| CN-109384752-A | A method of preparing 3- azido-methyl furan compound | 中国科学院大连化学物理研究所 | 2019-02-26 | — | — | CN | disclosed |
| CN-109384752-A | A method of preparing 3- azido-methyl furan compound | 中国科学院大连化学物理研究所 | 2019-02-26 | — | — | CN | disclosed |
| US-9351491-B2 | Inhibition and dispersion of biofilms in plants with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |
| US-9351491-B2 | Inhibition and dispersion of biofilms in plants with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-20110294668-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110294668-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| WO-2010077603-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |