Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23010396 | 0.81 | DGAT1 (0.35) | DGAT1CNR2NPSR1 | |
| SCHEMBL22906173 | 0.81 | DGAT1 (0.35) | DGAT1CNR2NPSR1 | |
| SCHEMBL3883297 | 0.78 | KDM4C (0.39) | — | |
| Hydrochloric Acid SCHEMBL7330618 | 0.78 | DPP4 (0.35) | DGAT1CNR2NPSR1 | |
| SCHEMBL7946781 | 0.75 | POLB (0.43) | — | |
| SCHEMBL2223240 | 0.72 | — | — | |
| SCHEMBL12563721 | 0.70 | ELANE (0.43) | DGAT1CNR2NPSR1 | |
| SCHEMBL4471302 | 0.70 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL6840349 | 0.69 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL18312018 | 0.69 | DGAT1 (0.39) | DGAT1CNR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590387-B1 | RING-OPENED AZLACTONE INITIATORS FOR NITROXIDE-MEDIATED POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2009-10-21 | — | — | EP | disclosed |
| EP-1620482-B1 | RING-OPENED AZLACTONE CHAIN TRANSFER AGENTS FOR RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2007-11-14 | — | — | EP | disclosed |