SCHEMBL1365566

SCHEMBL1365566

CCCCOC(=O)CCBr

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.57
ALDH1A1 P00352 3/20 0.52
NAAA Q02083 1/20 0.52
FAAH O00519 2/20 0.52
HTR2C P28335 1/20 0.50
ATM Q13315 1/20 0.48
DNM1 Q05193 1/20 0.47
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPK1 P28482 2/20 0.43
PAM P19021 2/20 0.42
HCAR2 Q8TDS4 1/20 0.42
MAPT P10636 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11371643 0.94 NAAA (0.61) DGKAALDH1A1NAAAFAAHHTR2C
SCHEMBL31024469 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL11373222 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL31024418 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL21811635 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL21811834 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL11783292 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL21811645 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL21811475 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1
SCHEMBL11785263 0.92 NAAA (0.64) DGKANAAAFAAHHTR2CDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110615859-B Preparation method of sodium gluconate 鲁南制药集团股份有限公司 2023-10-20 CN claimed
US-12390532-B2 ALK protein regulator and anti-tumor application thereof SHANGHAITECH UNIVERSITY (CN) 2025-08-19 US disclosed
WO-2025096653-A1 COMPOSITIONS AND INHIBITORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
WO-2025064788-A2 CCR5 CONJUGATES AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-03-27 WO disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
CN-117715903-A Cereblon binding compounds, compositions thereof, and methods for their use in therapy 新基公司 2024-03-15 CN disclosed
CN-110615859-B Preparation method of sodium gluconate 鲁南制药集团股份有限公司 2023-10-20 CN disclosed
WO-2023110970-A1 MACROCYCLIC BTK INHIBITORS NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) 2023-06-22 WO disclosed
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-07 US disclosed
CN-113166036-A Photopolymerisable sensitizers having migration resistance 川崎化成工业株式会社 2021-07-23 CN disclosed
WO-2005121207-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121204-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
CN-1438991-A Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase PFIZER CIMITED (US) 2003-08-27 CN disclosed
EP-1196436-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE Bristol-Myers Squibb Pharma Company (US) 2002-04-17 EP disclosed
WO-2001002424-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE DU PONT PHARMACEUTICALS COMPANY (US) 2001-01-11 WO disclosed
US-4281010-A FOR INCREASING BLOOD CIRCULATION DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-07-28 US disclosed
US-4254269-A PRECURSERS FOR CARDIOVASCULAR DRUGS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-03-03 US disclosed
US-4206213-A IMPROVING PERIPHERAL AND CEREBRAL CIRCULATION DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-06-03 US disclosed
US-4175088-A Process for the production of [1,1-dithienyl-(3)-1-hydroxypropyl-(3)]-[1-phenyl-1-hydroxypropyl-(2)]-amine and [1,1-dithienyl-(3)-propen-(1)-yl-(3)]-[1-phenylpropyl-(2)]-amine DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390532-B2 ALK protein regulator and anti-tumor application thereof ALK, MYC, ALKBH3 DGKA 1157/4885ALDH1A1 1743/4885NAAA 3266/4885
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA DGKA 2032/4885ALDH1A1 838/4885NAAA 1666/4885
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER F12, F10, PCNA DGKA 2032/4885ALDH1A1 838/4885NAAA 1666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.