Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.75 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.75 |
| ▸ | SHBG | P04278 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | STS | P08842 | 4/20 | 0.75 |
| ▸ | PGR | P06401 | 4/20 | 0.75 |
| ▸ | AR | P10275 | 4/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.75 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.75 |
| ▸ | SNCA | P37840 | 3/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | HTR2B | P41595 | 3/20 | 0.75 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.75 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13752801 | 1.00 | ESR1 (0.75) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL8242001 | 0.87 | ESR1 (0.72) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL4391235 | 0.87 | ESR1 (0.72) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL18372494 | 0.87 | ESR1 (0.72) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL5525067 | 0.87 | ESR1 (0.75) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL1236350 | 0.87 | ESR1 (0.75) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL14924234 | 0.87 | ESR1 (0.75) | ESR1ESR2SHBGHSD17B10LMNA | |
| SCHEMBL12888972 | 0.87 | ESR1 (0.75) | ESR1ESR2SHBGHSD17B10LMNA | |
| Estrone SCHEMBL5028951 | 0.86 | CYP19A1 (1.00) | ESR1ESR2SHBGHSD17B10LMNA | |
| Estrone SCHEMBL7831317 | 0.86 | CYP19A1 (1.00) | ESR1ESR2SHBGHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246850-A1 | METHOD FOR BIOCATALYSIS USING FILAMENTOUS FUNGI | UNIVERSITY OF THE WEST INDIES, A REGIONAL INSTITUTION, ESTABLISHED BY ROYAL CHARTER (JM) | 2009-10-01 | — | — | US | disclosed |