Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655889 | 0.89 | PPARG (0.53) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4073436 | 0.86 | PPARG (0.56) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4082101 | 0.86 | PPARA (0.67) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7068947 | 0.81 | PPARA (0.46) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13655922 | 0.80 | PPARA (0.47) | PPARGPPARAADRB2ADRB1ADRB3 | |
| SCHEMBL13655828 | 0.80 | PPARA (0.47) | PPARGPPARAADRB2ADRB1ADRB3 | |
| SCHEMBL13762777 | 0.78 | PPARA (0.67) | PPARGPPARAL3MBTL1CA12CA1 | |
| SCHEMBL13655824 | 0.78 | PPARG (0.43) | PPARGPPARANPC1RAB9AL3MBTL1 | |
| SCHEMBL5306788 | 0.77 | PPARG (0.53) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7068949 | 0.76 | NPC1 (0.46) | PPARGPPARANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7314889-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2008-01-01 | — | — | US | disclosed |