Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082101 | 0.90 | PPARA (0.67) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13655826 | 0.89 | PPARG (0.48) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4073436 | 0.88 | PPARG (0.56) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7068947 | 0.83 | PPARA (0.46) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13655823 | 0.81 | PPARA (0.50) | PPARGPPARAMAPT | |
| SCHEMBL13655792 | 0.81 | PPARA (0.50) | PPARGPPARAMAPT | |
| SCHEMBL7068949 | 0.80 | NPC1 (0.46) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5306788 | 0.79 | PPARG (0.53) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| Arginine SCHEMBL4085902 | 0.78 | PPARA (0.51) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| Arginine SCHEMBL4076394 | 0.78 | PPARA (0.51) | PPARGPPARANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7314889-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2008-01-01 | — | — | US | disclosed |