Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 16/20 | 0.49 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017817 | 0.90 | CALCRL (0.55) | CALCRLRAMP1 | |
| SCHEMBL13655701 | 0.90 | CALCRL (0.49) | CALCRLRAMP1KDM4E | |
| SCHEMBL14044248 | 0.90 | CALCRL (0.52) | CALCRLRAMP1 | |
| SCHEMBL14044251 | 0.89 | CALCRL (0.51) | CALCRLRAMP1 | |
| SCHEMBL13655714 | 0.88 | CALCRL (0.49) | CALCRLRAMP1 | |
| SCHEMBL13772886 | 0.88 | CALCRL (0.52) | CALCRLRAMP1 | |
| SCHEMBL14044249 | 0.87 | CALCRL (0.52) | CALCRLRAMP1 | |
| SCHEMBL13772873 | 0.87 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL14016560 | 0.86 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL14017700 | 0.86 | CALCRL (0.61) | CALCRLRAMP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108648-A1 | Selected CGRP antagonists, method for their manufacture and use as medicines | Boehringer Ingelheim International GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |