Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066597 | 0.92 | KIF11 (0.73) | KIF11KCNH2 | |
| SCHEMBL4060594 | 0.92 | KIF11 (0.73) | KIF11KCNH2 | |
| SCHEMBL14273871 | 0.92 | KIF11 (0.67) | KIF11KCNH2 | |
| SCHEMBL4065376 | 0.91 | KIF11 (0.74) | KIF11KCNH2 | |
| SCHEMBL4058935 | 0.89 | KIF11 (0.72) | KIF11KCNH2 | |
| SCHEMBL6205428 | 0.88 | KIF11 (0.77) | KIF11KCNH2 | |
| SCHEMBL4063773 | 0.88 | KIF11 (0.77) | KIF11KCNH2 | |
| SCHEMBL4061142 | 0.88 | KIF11 (0.77) | KIF11KCNH2 | |
| SCHEMBL4063362 | 0.88 | KIF11 (0.76) | KIF11KCNH2 | |
| SCHEMBL4061824 | 0.88 | KIF11 (0.70) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2009-10-21 | — | — | EP | disclosed |
| US-7348440-B2 | Kinesin spindle protein (KSP) inhibitors, e.g., 4-(2,5-Difluorophenyl)-N-[(3S,4S)-3-fluoropiperidin-4-yl]-2-hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1N-pyrrole-1-carboxamide, and a carrier; antiproliferative and -carcinogenic agents; side effects reduction; used with an estrogen receptor modulator | MERCK & CO., INC. (US) | 2008-03-25 | — | — | US | disclosed |