Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656048 | 0.86 | SIRT6 (0.55) | SIRT6SIRT1GRIA1GRIN1GRIN2A | |
| SCHEMBL22929126 | 0.78 | TSHR (0.42) | TSHRALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL16489221 | 0.77 | TSHR (0.66) | TSHRALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL16328487 | 0.77 | SIRT6 (0.34) | SIRT6SIRT1GRIA1PSMB11PSMD11 | |
| SCHEMBL16328495 | 0.77 | SIRT6 (0.34) | SIRT6SIRT1GRIA1PSMB11PSMD11 | |
| SCHEMBL16328488 | 0.77 | SIRT6 (0.34) | SIRT6SIRT1GRIA1PSMB11PSMD11 | |
| SCHEMBL16328489 | 0.77 | SIRT6 (0.34) | SIRT6SIRT1GRIA1PSMB11PSMD11 | |
| SCHEMBL10020956 | 0.76 | TSHR (0.39) | TSHRALDH1A1HPGDTLR2CHRNA1 | |
| SCHEMBL13656046 | 0.75 | HPGD (0.32) | GRIA1TSHRALDH1A1HPGD | |
| SCHEMBL13043697 | 0.73 | TSHR (0.34) | TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258416-A1 | POLYMER MICELLE COMPLEX INCLUDING NUCLEIC ACID | THE UNIVERSITY OF TOKYO (JP) | 2009-10-15 | — | — | US | disclosed |