Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.68 |
| ▸ | RXRA | P19793 | 1/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.68 |
| ▸ | CDK2 | P24941 | 1/20 | 0.68 |
| ▸ | RXRB | P28702 | 1/20 | 0.68 |
| ▸ | RXRG | P48443 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13470062 | 0.95 | KARS1 (0.65) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL14654982 | 0.94 | KARS1 (0.63) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL13656179 | 0.94 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL15072075 | 0.94 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL13656177 | 0.92 | KARS1 (0.71) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL13454807 | 0.92 | KARS1 (0.65) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL13454813 | 0.91 | KARS1 (0.64) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL16151866 | 0.91 | KARS1 (0.64) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL14826750 | 0.91 | KARS1 (0.64) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL13454818 | 0.91 | KARS1 (0.64) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604863-B2 | Primer layer of a film forming resin and an isocyanate silane and a reaction product of aminosilane and epoxysilane; and hot melt layer formed on the primer layer using a hot melt composition containing an aromatic polyester | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20080081194-A1 | COMPOSITE OF GLASS AND HOT MELT COMPOSITION AND METHOD OF PRODUCING THE SAME | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2008-04-03 | — | — | US | disclosed |