Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18622399 | 0.87 | MAPK1 (0.31) | — | |
| SCHEMBL12040128 | 0.78 | — | — | |
| SCHEMBL12040066 | 0.78 | — | — | |
| SCHEMBL19418565 | 0.76 | MAPK1 (0.44) | — | |
| SCHEMBL11923153 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL12040132 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL26854553 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL18789521 | 0.73 | LMNA (0.31) | — | |
| SCHEMBL11922105 | 0.72 | MAPK1 (0.44) | TSHR | |
| SCHEMBL11922098 | 0.72 | MAPK1 (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605176-B2 | β-ketoamide compounds with MCH antagonistic activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-20 | — | — | US | disclosed |