Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15163384 | 0.89 | KCNH2 (0.45) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| SCHEMBL13656360 | 0.88 | HRH3 (0.46) | HRH3KCNH2KDM1AUSP30GPR119 | |
| Hydrochloric Acid SCHEMBL3126726 | 0.88 | KCNH2 (0.44) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| SCHEMBL15163479 | 0.88 | HRH3 (0.44) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| Hydrochloric Acid SCHEMBL1618281 | 0.87 | HRH3 (0.43) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| SCHEMBL3124752 | 0.87 | KCNH2 (0.48) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| Hydrochloric Acid SCHEMBL3122612 | 0.87 | HRH3 (0.43) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| Hydrochloric Acid SCHEMBL3132895 | 0.86 | KCNH2 (0.47) | HRH3KCNH2LTA4HKDM1AUSP30 | |
| SCHEMBL1619397 | 0.82 | HRH3 (0.50) | HRH3KCNH2KDM1AUSP30HRH2 | |
| SCHEMBL1619391 | 0.81 | KCNH2 (0.48) | HRH3KCNH2KDM1AUSP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270383-A1 | Novel Oxabispidine Compounds And Their Use In The Treatment Of Cardiac Arrhythmias | ASTRAZENECA AB (SE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270383-A1 | Novel Oxabispidine Compounds And Their Use In The Treatment Of Cardiac Arrhythmias | KCNH1, RYR1, CACNA1E | HRH3 437/4885KCNH2 8/4885LTA4H 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.