SCHEMBL13656576

SCHEMBL13656576

CN(C)c1ccc2c(c1)c(=O)n(-c1ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(N)=O)cc1)c(=O)n2C

nearest known ligand 0.86

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 20/20 0.86
ITGB7 P26010 19/20 0.86
ITGB1 P05556 19/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3005744 0.93 ITGA4 (1.00) ITGA4ITGB7ITGB1
SCHEMBL29082839 0.93 ITGA4 (1.00) ITGA4ITGB7ITGB1
SCHEMBL12955399 0.91 ITGA4 (0.85) ITGA4ITGB7ITGB1
SCHEMBL10329624 0.91 ITGA4 (0.85) ITGA4ITGB7ITGB1
SCHEMBL13656581 0.90 ITGA4 (0.85) ITGA4ITGB7ITGB1
SCHEMBL13376853 0.88 ITGA4 (0.80) ITGA4ITGB7ITGB1
SCHEMBL13656586 0.88 ITGA4 (0.79) ITGA4ITGB7ITGB1
SCHEMBL13819221 0.88 ITGA4 (0.90) ITGA4ITGB7ITGB1
SCHEMBL13376836 0.87 ITGA4 (0.66) ITGA4ITGB7ITGB1
SCHEMBL13819225 0.86 ITGA4 (0.88) ITGA4ITGB7ITGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605165-B2 Phenylalanine derivatives AJINOMOTO CO., INC. (JP) 2009-10-20 US disclosed
US-7605165-B2 Phenylalanine derivatives AJINOMOTO CO., INC. (JP) 2009-10-20 US disclosed