Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601220 | 0.93 | NQO2 (0.49) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL8018113 | 0.88 | KCNA5 (0.56) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL30159605 | 0.88 | KCNA5 (0.56) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL18300396 | 0.85 | KLKB1 (0.46) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL30454240 | 0.85 | KCNA5 (0.52) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL6874894 | 0.85 | KCNA5 (0.52) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL17448537 | 0.85 | AAK1 (0.50) | KCNA5KDM4AHDAC10HDAC6NAMPT | |
| SCHEMBL13315241 | 0.85 | KDM4A (0.46) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL6018563 | 0.84 | KCNA5 (0.46) | NQO2KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL6018224 | 0.83 | KCNA5 (0.46) | NQO2KCNA5KDM4AHDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605182-B2 | drug conjugate with a marker for imaging to detect by fluorescence, X-ray, computerized tomography, magnetic resonance imaging (MRI), radio-isotope scan, single photon emission tomography (SPECT) or positron emission tomography (PET scan); targeting anticancer drugs to the tumor in body | APOSENSE LTD. (IL) | 2009-10-20 | — | — | US | disclosed |
| US-20070031326-A1 | Compounds that selectively bind to membranes of apoptotic cells | NEUROSURVIVAL TECHNOLOGIES, LTD. (IL) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031326-A1 | Compounds that selectively bind to membranes of apoptotic cells | BAD, BID, MCL1 | NQO2 3775/4885KCNA5 3555/4885KDM4A 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.