Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656743 | 0.93 | NQO2 (0.51) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL5792738 | 0.85 | KCNA5 (0.52) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL16415869 | 0.83 | RPS6KA1 (0.49) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL8018113 | 0.81 | KCNA5 (0.56) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL30159605 | 0.81 | KCNA5 (0.56) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL13612034 | 0.81 | MEN1 (0.39) | NQO2MEN1GAAKMT2ACA2 | |
| SCHEMBL12305689 | 0.80 | KCNA5 (0.60) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL18300396 | 0.79 | KLKB1 (0.46) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL6874894 | 0.79 | KCNA5 (0.52) | NQO2KCNA5NAMPTHDAC10HDAC6 | |
| SCHEMBL30454240 | 0.79 | KCNA5 (0.52) | NQO2KCNA5NAMPTHDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |