Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054611 | 0.89 | NAMPT (0.64) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11561275 | 0.84 | NAMPT (0.64) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2056379 | 0.84 | NAMPT (0.67) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8211195 | 0.83 | NAMPT (0.68) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5286555 | 0.83 | NAMPT (0.68) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11563747 | 0.81 | NAMPT (0.77) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4822201 | 0.81 | NAMPT (0.65) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11814496 | 0.80 | NAMPT (0.68) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11556886 | 0.80 | NAMPT (0.75) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11818293 | 0.80 | KMT2A (0.65) | NAMPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253766-A1 | THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253766-A1 | THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS | TFPI, F12, F11 | NAMPT 3837/4885KMT2A 2659/4885MEN1 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.