Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657333 | 0.97 | KMT2A (0.56) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL16885059 | 0.97 | KMT2A (0.52) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL16425816 | 0.96 | KMT2A (0.53) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL19982368 | 0.96 | KMT2A (0.53) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL16885049 | 0.96 | KMT2A (0.53) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL19982370 | 0.95 | KMT2A (0.52) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL23227544 | 0.94 | KMT2A (0.49) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL13657338 | 0.93 | KMT2A (0.48) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL14346685 | 0.93 | KMT2A (0.48) | KMT2AMAPTCYP3A4MEN1TDP1 | |
| SCHEMBL15855597 | 0.92 | MAPT (0.50) | KMT2AMAPTCYP3A4MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |
| US-7597942-B2 | Polymerisable liquid crystal material | MERCK PATENT GMBH (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20080143943-A1 | Polymerisable Liquid Crystal Material | MERCK PATENT GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080143943-A1 | Polymerisable Liquid Crystal Material | VCL, LCT, LCP1 | KMT2A 2933/4885MAPT 157/4885CYP3A4 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.