SCHEMBL13658166

SCHEMBL13658166

c1ccc(CCN(Cc2ccccc2)Cc2ccc(-c3ccc(CN(CCc4ccccc4)Cc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 5/20 0.56
OPRM1 P35372 4/20 0.56
OPRD1 P41143 4/20 0.56
L3MBTL1 Q9Y468 2/20 0.51
HRH3 Q9Y5N1 3/20 0.50
TAAR1 Q96RJ0 2/20 0.50
TRPM8 Q7Z2W7 1/20 0.47
TRPV1 Q8NER1 1/20 0.47
BCHE P06276 1/20 0.47
AOC3 Q16853 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12049809 0.94 OPRK1 (0.61) OPRK1OPRM1OPRD1L3MBTL1TAAR1
SCHEMBL231061 0.91 OPRK1 (0.63) OPRK1OPRM1OPRD1L3MBTL1TAAR1
SCHEMBL13049987 0.89 OPRK1 (0.67) OPRK1OPRM1OPRD1L3MBTL1TAAR1
SCHEMBL13658167 0.89 OPRK1 (0.57) OPRK1OPRM1OPRD1HRH3TAAR1
SCHEMBL14047033 0.87 OPRK1 (0.69) OPRK1OPRM1OPRD1L3MBTL1TAAR1
SCHEMBL12679040 0.84 TAAR1 (0.60) HRH3TAAR1AOC3
SCHEMBL3158647 0.84 MAOB (0.63) OPRK1OPRM1OPRD1L3MBTL1TAAR1
SCHEMBL6621416 0.84 FNTA (0.54) OPRK1OPRM1OPRD1L3MBTL1TAAR1
SCHEMBL15159196 0.84 CYP2C19 (0.50) OPRK1OPRM1OPRD1L3MBTL1HRH3
SCHEMBL12049808 0.82 OPRK1 (0.63) OPRK1OPRM1OPRD1TAAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343697-B2 Electrophotographic photoconductor and image forming apparatus provided with the same SHARP KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-8343697-B2 Electrophotographic photoconductor and image forming apparatus provided with the same SHARP KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-20090257777-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-10-15 US disclosed
US-20090257777-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-10-15 US disclosed