Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183154 | 0.87 | HSP90AA1 (0.54) | HSP90AA1 | |
| SCHEMBL13658320 | 0.85 | HSP90AA1 (0.49) | HSP90AA1 | |
| SCHEMBL12411983 | 0.74 | HSP90AA1 (0.51) | HSP90AA1 | |
| SCHEMBL2184016 | 0.74 | HSP90AA1 (0.57) | HSP90AA1 | |
| SCHEMBL12411684 | 0.73 | HSP90AA1 (0.65) | HSP90AA1 | |
| SCHEMBL13658334 | 0.73 | HSP90AA1 (0.39) | HSP90AA1 | |
| SCHEMBL2181503 | 0.72 | HSP90AA1 (0.56) | HSP90AA1 | |
| SCHEMBL2181425 | 0.72 | HSP90AA1 (0.52) | HSP90AA1 | |
| SCHEMBL2180152 | 0.72 | HSP90AA1 (0.52) | HSP90AA1 | |
| SCHEMBL13658219 | 0.72 | HSP90AA1 (0.55) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122034-A2 | NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | WO | disclosed |