Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20306785 | 1.00 | HPGD (0.46) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL14308340 | 1.00 | HPGD (0.46) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL13986909 | 0.82 | MEN1 (0.43) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL20050181 | 0.81 | MEN1 (0.49) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL23073349 | 0.77 | HPGD (0.46) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL9910733 | 0.77 | HPGD (0.46) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL13921738 | 0.77 | HPGD (0.46) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL18464425 | 0.76 | MEN1 (0.45) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL20959996 | 0.74 | BTN3A1 (0.54) | HPGDNPSR1MEN1KMT2ALMNA | |
| SCHEMBL13656424 | 0.74 | BTN3A1 (0.54) | HPGDNPSR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605144-B2 | Enzyme catalyzed therapeutic compounds | CELMED ONCOLOGY (USA), INC. (CA) | 2009-10-20 | — | — | US | disclosed |
| US-7462605-B2 | Phosphoramidate compounds and methods of use | CELMED ONCOLOGY (USA), INC. (CA) | 2008-12-09 | — | — | US | disclosed |