Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18464425 | 0.82 | MEN1 (0.45) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL13660304 | 0.81 | HPGD (0.46) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL14308340 | 0.81 | HPGD (0.46) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL20306785 | 0.81 | HPGD (0.46) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL13986909 | 0.79 | MEN1 (0.43) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL18948777 | 0.78 | BTN3A1 (0.41) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL4334505 | 0.78 | KDM4E (0.55) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL16576300 | 0.77 | BTN3A1 (0.53) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL25709714 | 0.77 | BTN3A1 (0.53) | MEN1KMT2ANPSR1KDM4EL3MBTL1 | |
| SCHEMBL13660267 | 0.77 | BTN3A1 (0.53) | MEN1KMT2ANPSR1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067241-A1 | MACROHETEROCYCLIC NUCLEOSIDE DERIVATIVES AND THEIR ANALOGUES, PRODUCTION AND USE THEREOF | ASAVI, LLC (US) | 2018-04-12 | — | — | WO | disclosed |