SCHEMBL13660710

SCHEMBL13660710

CCCCNC(=O)C(C)N

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.58
SLC15A1 P46059 1/20 0.53
RRM1 P23921 1/20 0.53
GNAI3 P08754 1/20 0.50
GNAO1 P09471 1/20 0.50
GNAI1 P63096 1/20 0.50
DPP8 Q6V1X1 1/20 0.49
EPHX1 P07099 6/20 0.48
S1PR2 O95136 2/20 0.46
S1PR1 P21453 2/20 0.46
S1PR3 Q99500 2/20 0.46
S1PR5 Q9H228 1/20 0.46
MMP8 P22894 1/20 0.46
REN P00797 2/20 0.46
ACHE P22303 1/20 0.45
MMP2 P08253 1/20 0.45
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22987681 1.00 DPP7 (0.58) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL10709517 1.00 DPP7 (0.58) DPP7SLC15A1RRM1GNAI3GNAO1
Hydrochloric Acid SCHEMBL10704418 0.98 DPP7 (0.56) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL7066329 0.94 DPP7 (0.67) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL7700853 0.94 DPP7 (0.67) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL6238460 0.92 DPP7 (0.65) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL20801620 0.92 DPP7 (0.65) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL20707200 0.92 DPP7 (0.65) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL30865485 0.92 DPP7 (0.65) DPP7SLC15A1RRM1GNAI3GNAO1
SCHEMBL6413585 0.92 DPP7 (0.65) DPP7SLC15A1RRM1GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023513-A9 STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE UNIVERSITY OF MASSACHUSETTS (US) 2023-06-01 WO disclosed
WO-2023023513-A1 STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE UNIVERSITY OF MASSACHUSETTS (US) 2023-02-23 WO disclosed
EP-3888691-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2021-10-06 EP disclosed
WO-2018086139-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2018-05-17 WO disclosed
US-7608723-B2 N-(3-aminopropyl)-N-[(1R)-1-(1-benzyl-1H-benzimidazol-2-yl)-2-methylpropyl]-4-chlorobenzamide;kinesin spindle protein modulators; anticarcinogenic agents; in vivo stability, bio-availability; diagnosis/medical/;antitumor agents hyperplasia; restinosis; antiinflammatory agents; cardiac hypertrophy NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2009-10-27 US disclosed