Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 11/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881617 | 0.90 | APP (0.44) | PDCD1CD274TLR9TLR7APP | |
| SCHEMBL1262023 | 0.81 | PDCD1 (0.52) | PDCD1CD274TLR9TLR7TLR8 | |
| SCHEMBL15164318 | 0.81 | PDCD1 (0.52) | PDCD1CD274TLR9TLR7APP | |
| SCHEMBL30785589 | 0.81 | PDCD1 (0.52) | PDCD1CD274TLR9TLR7ALDH1A1 | |
| SCHEMBL12491614 | 0.81 | PDCD1 (0.69) | PDCD1CD274TLR9TLR7NPC1 | |
| SCHEMBL4761746 | 0.81 | PDCD1 (0.52) | PDCD1CD274TLR9TLR7TLR8 | |
| Hydrochloric Acid SCHEMBL1263591 | 0.80 | PDCD1 (0.51) | PDCD1CD274TLR9TLR7TLR8 | |
| SCHEMBL13667275 | 0.80 | GAA (0.53) | APPGAAMGAMSIMGAM2 | |
| SCHEMBL5644831 | 0.78 | PDCD1 (0.50) | PDCD1CD274TLR9TLR7NPC1 | |
| SCHEMBL1261819 | 0.78 | PDCD1 (0.49) | PDCD1CD274TLR9TLR7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270447-A1 | 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof | WYETH (US) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270447-A1 | 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof | CYP2U1, SEC22B, SEC63 | PDCD1 2060/4885CD274 4121/4885TLR9 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.