Sugi Predict

Sugi Predict / Targets / SEC63

SEC63

Translocation protein SEC63 homolog · Q9UGP8 · SEC63 on Sugi Atlas →

0 patent compounds predicted against SEC63, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SEC63 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers PHASE1/PHASE2RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients PHASE1UNKNOWN
A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors PHASE1COMPLETED
Phase I Study of SC-43 Oral Solution in Subjects With Refractory Solid Tumors PHASE1WITHDRAWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients nanRECRUITING
Quantification of GADD34 Expression in RA nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Autophagy Bladder Cancer nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Identification of New Diagnostic Protein Markers for Colorectal Cancer nanCOMPLETED
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment. nanACTIVE_NOT_RECRUITING
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA） nanRECRUITING
Gene Expression in Inflammatory Bowel Disease nanENROLLING_BY_INVITATION
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
sCD163 in ALS Patients nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Identification of New Biomarkers of Insulin Resistance nanACTIVE_NOT_RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Childhood-Onset Essential Hypertension Natural History Study nanRECRUITING
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children nanCOMPLETED
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING
Identification of a New Gene Involved in Hereditary Lipodystrophy nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SEC63 binder may also engage these)

ProteinNameSimilarity
Q5R660 — 1.000 Q5R660 →
Q8VHE0 — 1.000 Q8VHE0 →
A9JRA0 — 0.975 A9JRA0 →
Q8IWV8 — 0.973 Q8IWV8 →
Q108U3 — 0.972 Q108U3 →
Q09YI5 — 0.971 Q09YI5 →
Q09YJ7 — 0.970 Q09YJ7 →
Q07E08 — 0.970 Q07E08 →
Q2IBE0 — 0.970 Q2IBE0 →
Q2QLB7 — 0.970 Q2QLB7 →
Q00PJ0 — 0.970 Q00PJ0 →
Q07DV5 — 0.970 Q07DV5 →
Q07E45 — 0.970 Q07E45 →
Q07DW9 — 0.969 Q07DW9 →
A4D7R9 — 0.969 A4D7R9 →
A0M8S0 — 0.969 A0M8S0 →
Q07DY8 — 0.969 Q07DY8 →
Q2IBA8 — 0.969 Q2IBA8 →
Q9NRC1 — 0.969 Q9NRC1 →
A0M8T1 — 0.969 A0M8T1 →
Q09YK8 — 0.969 Q09YK8 →
Q2IBE8 — 0.968 Q2IBE8 →
Q2QL86 — 0.968 Q2QL86 →
Q08BT5 — 0.968 Q08BT5 →
Q9R1D7 — 0.968 Q9R1D7 →
Q9BZ29 — 0.968 Q9BZ29 →
Q9UPW8 — 0.967 Q9UPW8 →
Q07DX8 — 0.967 Q07DX8 →
Q2QLG2 — 0.967 Q2QLG2 →
USP9X Ubiquitin carboxyl-terminal hydrolase 9X 0.967 landscape →