Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986168 | 0.94 | MAPT (0.38) | KMT2AMAPTPPARDTDP1L3MBTL1 | |
| SCHEMBL13664646 | 0.92 | PPARD (0.39) | KMT2AMAPTPPARDTDP1L3MBTL1 | |
| SCHEMBL13664625 | 0.90 | POLB (0.43) | KMT2AMAPTPPARDTDP1L3MBTL1 | |
| SCHEMBL13664634 | 0.85 | KMT2A (0.42) | KMT2AMAPTTDP1LMNAPOLB | |
| SCHEMBL13664645 | 0.84 | KMT2A (0.44) | KMT2AMAPTTDP1L3MBTL1LMNA | |
| SCHEMBL11986094 | 0.84 | POLB (0.43) | KMT2AMAPTTDP1LMNAGBA1 | |
| SCHEMBL14590324 | 0.83 | KMT2A (0.51) | KMT2AMAPTTDP1L3MBTL1LMNA | |
| SCHEMBL5961817 | 0.83 | KMT2A (0.39) | KMT2AMAPTPPARDTDP1L3MBTL1 | |
| SCHEMBL12733732 | 0.82 | KMT2A (0.35) | KMT2AMAPTPPARDLMNAGBA1 | |
| SCHEMBL11986167 | 0.82 | PPARD (0.40) | KMT2AMAPTPPARDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7597945-B2 | Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties | CHISSO CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |