SCHEMBL11986167

SCHEMBL11986167

C=C(C(=O)OCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCOC(=O)C(=C)C(F)(F)F)cc3)c(C)c2)cc1)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 3/20 0.40
MAPT P10636 3/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 7/20 0.35
LMNA P02545 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
GBA1 P04062 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14088561 0.89 POLB (0.41) PPARDMAPTKDM4EPOLBMAPK1
SCHEMBL14088566 0.89 HTT (0.46) PPARDMAPTPOLBKMT2ALMNA
SCHEMBL11986168 0.88 MAPT (0.38) PPARDMAPTKDM4EPOLBMAPK1
SCHEMBL14088404 0.87 RXRA (0.36) PPARDMAPTKDM4EPOLBMAPK1
SCHEMBL11986094 0.86 POLB (0.43) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL16746159 0.86 KMT2A (0.40) MAPTKMT2ALMNATDP1L3MBTL1
SCHEMBL19757163 0.83 POLB (0.41) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL13664646 0.83 PPARD (0.39) PPARDMAPTKMT2ALMNATDP1
SCHEMBL14026812 0.83 KMT2A (0.44) MAPTKDM4EPOLBKMT2ATDP1
SCHEMBL13664631 0.82 KMT2A (0.39) PPARDMAPTKDM4EPOLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed
US-7410677-B2 Organosilicon compound-containing polymerizable liquid-crystal composition CHISSO CORPORATION (JP) 2008-08-12 US disclosed