Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | S100A4 | P26447 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15432851 | 0.98 | CYP2C19 (0.49) | CYP2C19MIFUSP8USP7NPC1 | |
| SCHEMBL11351193 | 0.81 | CYP2C19 (0.50) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL13668026 | 0.79 | CYP2C19 (0.56) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL13179763 | 0.77 | CYP2C19 (0.57) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL9064366 | 0.76 | MIF (0.42) | MIFALDH1A1CYP3A4TDP1TP53 | |
| SCHEMBL10617594 | 0.76 | CYP2C19 (0.51) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL10617590 | 0.76 | CYP2C19 (0.51) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL542807 | 0.75 | MAPK1 (0.50) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL21084970 | 0.75 | CYP2C19 (0.54) | CYP2C19USP8USP7NPC1RAB9A | |
| SCHEMBL940920 | 0.75 | MAPK1 (0.50) | CYP2C19USP8USP7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270372-A1 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET (FR) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270372-A1 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS | MC4R, MC3R, MC1R | CYP2C19 801/4885MIF 277/4885USP8 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.