SCHEMBL542807

SCHEMBL542807

O=C=Nc1ccc2c(c1)C(=O)c1ccc(N=C=O)cc1C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 3/20 0.47
TRPA1 O75762 1/20 0.47
TSHR P16473 2/20 0.43
CYP2C19 P33261 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
ESR1 P03372 1/20 0.41
UGT1A1 P22309 1/20 0.41
ESR2 Q92731 1/20 0.41
CYP1A2 P05177 1/20 0.40
NPC1 O15118 3/20 0.38
ALDH1A1 P00352 3/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ELANE P08246 1/20 0.38
TP53 P04637 1/20 0.38
BCL2 P10415 2/20 0.35
MCL1 Q07820 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940920 0.96 MAPK1 (0.50) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL11351193 0.94 CYP2C19 (0.50) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL28562992 0.84 TDP1 (0.56) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL28448245 0.84 TDP1 (0.56) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL9480950 0.78 TDP1 (0.46) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL15432851 0.76 CYP2C19 (0.49) MAPK1TDP1CYP3A4TSHRCYP2C19
SCHEMBL2663488 0.75 CYP3A4 (0.41) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL13664662 0.75 CYP2C19 (0.51) MAPK1TDP1CYP3A4TSHRCYP2C19
SCHEMBL2770967 0.74 MAPK1 (0.73) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL2156677 0.74 MAPK1 (0.50) MAPK1TDP1CYP3A4TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570561-B2 Sizing agent for carbon fiber, carbon fiber with improved interfacial adhesion, polymerization reaction type carbon fiber-reinforced polymer composite material using same, and production method therefor KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2020-02-25 US claimed
US-20190284751-A1 SIZING AGENT FOR CARBON FIBER, CARBON FIBER WITH IMPROVED INTERFACIAL ADHESION, POLYMERIZATION REACTION TYPE CARBON FIBER-REINFORCED POLYMER COMPOSITE MATERIAL USING SAME, AND PRODUCTION METHOD THEREFOR KOREA INSTITUTE OF MATERIALS SCIENCE (KR) 2019-09-19 US claimed
EP-1915411-A1 NEW ORGANIC BOTTOM ANTIREFLECTIVE POLYMER COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2008-04-30 EP claimed
US-20070020557-A1 New organic bottom antireflective polymer compositions AZ ELECTRONIC MATERIALS USA CORP. 2007-01-25 US claimed
WO-2007010385-A1 NEW ORGANIC BOTTOM ANTIREFLECTIVE POLYMER COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-01-25 WO claimed
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
US-10570561-B2 Sizing agent for carbon fiber, carbon fiber with improved interfacial adhesion, polymerization reaction type carbon fiber-reinforced polymer composite material using same, and production method therefor KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2020-02-25 US disclosed
US-20190284751-A1 SIZING AGENT FOR CARBON FIBER, CARBON FIBER WITH IMPROVED INTERFACIAL ADHESION, POLYMERIZATION REACTION TYPE CARBON FIBER-REINFORCED POLYMER COMPOSITE MATERIAL USING SAME, AND PRODUCTION METHOD THEREFOR KOREA INSTITUTE OF MATERIALS SCIENCE (KR) 2019-09-19 US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
EP-2554392-B1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME MITSUBISHI PAPER MILLS LTD (JP) 2016-05-11 EP disclosed
US-8980790-B2 Thermosensitive multiple recording sheet and method for producing the same OJI PAPER CO., LTD. (JP) 2015-03-17 US disclosed
US-8847075-B2 Insulated wire FURUKAWA ELECTRIC CO., LTD. (JP) 2014-09-30 US disclosed
US-4123599-A PHENOLIC RESINS REACTED WITH ORGANIC DIISOCYANATES AND/OR POLYISOCYANTES IN THE PRESENCE OF METAL POWDERS AND/OR METAL OXIDE POWDERS CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-10-31 US disclosed
US-4108807-A REACTING A METALLATE WITH A PSEUDOHALIDE IN THE PRESENCE OF A PHENOL-SUBSTITUTED TERTIARY AMINE CATALYST CHEMIC-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-08-22 US disclosed
US-4108954-A Process of producing shaped structures of crosslinked elastomeric polyurethane CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-08-22 US disclosed
US-4098730-A Non-flammable organo-red mud polymers, some of which are electrically conductive, and process for their manufacture METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) 1978-07-04 US disclosed
US-4078086-A Anthraquinone-bis-amidines and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed
US-3932318-A COPOLYMERS WITH ISOCYANATES, CRYOGENIC POLYMERIZATION, NONFLAMMABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US disclosed
US-3931065-A POLYURETHANE-MODIFIED POLYISOCYANURATE FOAM AND A METHOD FOR THE PREPARATION THEREOF NISSHIN BOSEKI KABUSHIKI KAISHA (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570561-B2 Sizing agent for carbon fiber, carbon fiber with improved interfacial adhesion, polymerization reaction type carbon fiber-reinforced polymer composite material using same, and production method therefor NOTUM, MACF1, FAR1 MAPK1 2074/4885TDP1 3316/4885CYP3A4 796/4885
US-20190284751-A1 SIZING AGENT FOR CARBON FIBER, CARBON FIBER WITH IMPROVED INTERFACIAL ADHESION, POLYMERIZATION REACTION TYPE CARBON FIBER-REINFORCED POLYMER COMPOSITE MATERIAL USING SAME, AND PRODUCTION METHOD THEREFOR NOTUM, MACF1, FAR1 MAPK1 2074/4885TDP1 3316/4885CYP3A4 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.