Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713356 | 0.83 | GRIN2D (0.44) | IDH1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6346023 | 0.80 | DAO (0.63) | GRIA1GRIA2GRIA3GRIA4IDH1 | |
| SCHEMBL32662390 | 0.80 | DAO (0.63) | IDH1DAO | |
| SCHEMBL6521139 | 0.78 | IL4I1 (0.49) | IDH1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30162579 | 0.78 | IL4I1 (0.49) | IDH1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3719191 | 0.78 | IDH1 (0.50) | IDH1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL15690660 | 0.77 | DAO (0.64) | CHEK1CYP19A1FLT3HRH4HRH3 | |
| SCHEMBL6402311 | 0.77 | DAO (0.59) | GRIA1GRIA2GRIA3GRIA4CHEK1 | |
| SCHEMBL18548573 | 0.77 | CYP19A1 (0.49) | CHEK1IDH1HPGDTP53CYP19A1 | |
| SCHEMBL9293461 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128262-A1 | QUINOLONE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |