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Sugi Predict / Targets / IL4I1

IL4I1

L-amino-acid oxidase · Q96RQ9 · IL4I1 on Sugi Atlas →

1,850 patent compounds predicted against IL4I1, 990 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL27163306 SCHEMBL27163306 0.77 9/20
SCHEMBL27163079 SCHEMBL27163079 0.74 9/20
SCHEMBL27163789 SCHEMBL27163789 0.64 9/20
SCHEMBL27163158 SCHEMBL27163158 0.58 9/20
SCHEMBL27163162 SCHEMBL27163162 0.58 9/20
SCHEMBL27163300 SCHEMBL27163300 0.58 9/20
SCHEMBL27163220 SCHEMBL27163220 1.00 8/20
SCHEMBL27163156 SCHEMBL27163156 0.80 8/20
SCHEMBL27163127 SCHEMBL27163127 0.77 8/20
SCHEMBL27162916 SCHEMBL27162916 0.77 8/20
SCHEMBL27163187 SCHEMBL27163187 0.62 8/20
SCHEMBL27163582 SCHEMBL27163582 0.62 8/20
SCHEMBL27164223 SCHEMBL27164223 0.61 8/20
SCHEMBL27164229 SCHEMBL27164229 0.61 8/20
SCHEMBL27164232 SCHEMBL27164232 0.61 8/20
SCHEMBL27163527 SCHEMBL27163527 0.55 8/20
SCHEMBL27163134 SCHEMBL27163134 0.50 8/20
SCHEMBL27163138 SCHEMBL27163138 0.50 8/20
SCHEMBL27163580 SCHEMBL27163580 0.50 8/20
SCHEMBL27163698 SCHEMBL27163698 1.00 7/20

Clinical trials — most relevant to IL4I1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Predicting Response to Standardized Pediatric Colitis Therapy PHASE4COMPLETED
Pirfenidone LP or Collagen-polyvinylpyrrolidone in COVID-19 PHASE2/PHASE3COMPLETED
Study of Apremilast in Atopic or Contact Dermatitis PHASE2COMPLETED
Role of TLR4 in Environmental Asthma PHASE1COMPLETED
Expression of IL4 Induced Gene 1 in Patients With Cutaneous Melanoma: Value in Prognosis and/or in Predictive Response to Immune Checkpoint Inhibitors nanCOMPLETED
Preterm Arginine INTake Study nanCOMPLETED
Factors Involved in Asthma and Airway Inflammation nanCOMPLETED
Genetic Determinants of Ankylosing Spondylitis Severity nanCOMPLETED
Allergy and Immunology Natural History Study nanRECRUITING
Refractory Asthma Stratification Programme (RASP) Bronchoscopy Study nanUNKNOWN
The Genetics of Environmental Asthma nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery nanCOMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer nanUNKNOWN
Novel Genetic Disorders of the Immune System nanRECRUITING
Genetic Basis of Immunodeficiency nanRECRUITING
In Vivo Assessment of Histamine Pharmacodynamics nanWITHDRAWN
Collaborative Studies on the Genetics of Asthma (CSGA) nanCOMPLETED
NIAID Clinical Center Genomics Opportunity Protocol nanCOMPLETED
JAK-STAT Signalling Pathway in Familial Myeloproliferative Disorders nanCOMPLETED
T Cell Cytokine Changes During IL-4 Receptor Treatment for Asthma nanCOMPLETED
An Exploratory Study of Arginine Supplementation and the Postoperative Immune REsponse nanRECRUITING
Translational Study of the Effects of Neural Mobilization in Patients With Lomboisquiatalgia nanCOMPLETED
The Role of Ischaemia-reperfusion Injury in the Pathogenesis of Muscle Wasting After Thoracic Aortic Surgery nanCOMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study nanRECRUITING
Exploratory Evaluation of Biomarkers Associated With Treatment Response to Cosentyx (Secukinumab) in Psoriasis Patients nanCOMPLETED
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Effect of Arginine and Glutamine on Radiation-induced Oral Mucositis: a Trible Blinded Randomized Controlled Clinical Trial nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a IL4I1 binder may also engage these)

ProteinNameSimilarity
O09046 — 0.998 O09046 →
KDM1A Lysine-specific histone demethylase 1A 0.992 landscape →
Q90W54 — 0.991 Q90W54 →
Q8BJM7 — 0.991 Q8BJM7 →
B5AR80 — 0.990 B5AR80 →
Q6ZQ88 — 0.989 Q6ZQ88 →
P40126 — 0.989 P40126 →
Q8N3T1 — 0.988 Q8N3T1 →
Q00495 — 0.988 Q00495 →
K9N7B7 — 0.987 K9N7B7 →
Q8N490 — 0.987 Q8N490 →
A8QL52 — 0.987 A8QL52 →
Q95N00 — 0.987 Q95N00 →
SMOX Spermine oxidase 0.987 landscape →
Q3U435 — 0.987 Q3U435 →
Q5R607 — 0.987 Q5R607 →
Q6WP39 — 0.987 Q6WP39 →
Q6P996 — 0.987 Q6P996 →
A8QL51 — 0.987 A8QL51 →
Q60HF6 — 0.986 Q60HF6 →
GALNT6 Polypeptide N-acetylgalactosaminyltransferase 6 0.986 landscape →
P14617 — 0.986 P14617 →
Q9VPN2 — 0.986 Q9VPN2 →
O54732 — 0.986 O54732 →
KDM5D Lysine-specific demethylase 5D 0.986 landscape →
DHX30 ATP-dependent RNA helicase DHX30 0.986 landscape →
Q01634 — 0.986 Q01634 →
Q5M936 — 0.986 Q5M936 →
O75064 — 0.986 O75064 →
Q91ZT1 — 0.986 Q91ZT1 →