Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664818 | 0.93 | SLC6A2 (0.51) | MAPTSMN1; SMN2HTTMAPK1ESR2 | |
| SCHEMBL30208188 | 0.82 | MAPT (0.72) | MAPTSMN1; SMN2HTTMAPK1ALDH1A1 | |
| SCHEMBL15797078 | 0.82 | MAPT (0.72) | MAPTSMN1; SMN2HTTMAPK1ALDH1A1 | |
| SCHEMBL26629245 | 0.80 | NR1H2 (0.46) | MAPTSMN1; SMN2HTTESR2ALDH1A1 | |
| SCHEMBL31093400 | 0.80 | POLB (0.46) | MAPTSMN1; SMN2ESR2ALDH1A1GPR119 | |
| SCHEMBL31342592 | 0.78 | SUV39H2 (0.44) | MAPTESR2ALDH1A1GPR119LMNA | |
| SCHEMBL30962704 | 0.78 | MAPT (0.70) | MAPTSMN1; SMN2HTTESR2ALDH1A1 | |
| SCHEMBL20037632 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2ESR2ALDH1A1GPR119 | |
| SCHEMBL3608564 | 0.77 | USP30 (0.54) | MAPTSMN1; SMN2HTTMAPK1ALDH1A1 | |
| SCHEMBL13664698 | 0.76 | MEN1 (0.42) | ESR2GPR119MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |