Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664818 | 0.83 | SLC6A2 (0.51) | MEN1KMT2AGPR119ESR2SLC6A2 | |
| SCHEMBL13664691 | 0.76 | MAPT (0.50) | MEN1KMT2AGPR119ESR2SLC6A2 | |
| SCHEMBL13665296 | 0.75 | PIK3CD (0.41) | MEN1KMT2AGPR119ESR2SLC6A2 | |
| SCHEMBL27852746 | 0.75 | ALDH1A1 (0.54) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20929548 | 0.74 | NR1H2 (0.65) | MEN1KMT2AESR2NR1H2NPC1 | |
| Diphenylether SCHEMBL27989772 | 0.74 | MEN1 (0.55) | MEN1KMT2AGPR119CKS1BSKP1 | |
| SCHEMBL3872052 | 0.74 | ESR2 (0.56) | MEN1KMT2AESR2NR1H2PDK2 | |
| SCHEMBL1779308 | 0.74 | MAPK1 (0.55) | MEN1KMT2AGPR119PDK2NAMPT | |
| SCHEMBL14894490 | 0.73 | LMNA (0.43) | GPR119ESR2NR1H2USP30NPC1 | |
| SCHEMBL8250733 | 0.72 | MEN1 (0.47) | MEN1KMT2AGPR119PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |