Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | STK17B | O94768 | 1/20 | 0.48 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126784 | 0.84 | MEN1 (0.53) | STK17BSTK17ABRD4BCHECA1 | |
| SCHEMBL22121387 | 0.82 | HDAC3 (0.59) | — | |
| SCHEMBL10126690 | 0.82 | MTNR1A (0.60) | STK17BSTK17ABRD4CA1CA2 | |
| SCHEMBL13664868 | 0.81 | STK17B (0.55) | STK17BSTK17ABRD4CA1CA2 | |
| SCHEMBL16024065 | 0.81 | MAPT (0.51) | NQO2STK17BSTK17ABRD4PIM1 | |
| SCHEMBL3013509 | 0.80 | MAPT (0.51) | STK17BSTK17ABRD4CA1CA2 | |
| SCHEMBL28480597 | 0.80 | CYP1A2 (0.46) | ACACBEPHX1CA1CA2CA12 | |
| SCHEMBL7419088 | 0.80 | STK17B (0.50) | STK17BSTK17ABRD4CA1CA2 | |
| SCHEMBL21224591 | 0.80 | TDP1 (0.58) | BRD4CA1CA2CA12CA9 | |
| SCHEMBL17471214 | 0.80 | CA1 (0.49) | NQO2STK17BSTK17ABRD4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |