Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664588 | 0.77 | TAAR1 (0.45) | KDM4EALDH1A1HSD17B10HTTKMT2A | |
| SCHEMBL13664577 | 0.76 | TAAR1 (0.62) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL13664754 | 0.75 | TAAR1 (0.54) | KDM4EALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL16938461 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL16938462 | 0.68 | GRM1 (0.57) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL12330460 | 0.68 | KMT2A (0.51) | KDM4EALDH1A1HSD17B10HTTKMT2A | |
| SCHEMBL4114418 | 0.67 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HTTKMT2A | |
| SCHEMBL4075829 | 0.66 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10HTTKMT2A | |
| SCHEMBL4746162 | 0.66 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HTTKMT2A | |
| SCHEMBL15136984 | 0.65 | CTNNB1 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128262-A1 | QUINOLONE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |