Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664577 | 0.86 | TAAR1 (0.62) | TAAR1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL30162579 | 0.80 | IL4I1 (0.49) | ALDH1A1KDM4EMAPTHPGDHTT | |
| SCHEMBL6521139 | 0.80 | IL4I1 (0.49) | ALDH1A1KDM4EMAPTHPGDHTT | |
| SCHEMBL13664588 | 0.77 | TAAR1 (0.45) | TAAR1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL13664759 | 0.75 | KDM4E (0.49) | TAAR1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL4114418 | 0.73 | KDM4E (0.71) | TAAR1MEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4805202 | 0.73 | POLB (0.59) | TAAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13664756 | 0.72 | TSHR (0.64) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL13664567 | 0.71 | KDM4E (0.58) | TAAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13664670 | 0.71 | GRIA1 (0.47) | PIM1ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128262-A1 | QUINOLONE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |