SCHEMBL13664797

SCHEMBL13664797

NC(=O)CCc1ccc(OCCCc2ccccc2)c(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.47
S1PR1 P21453 3/20 0.47
FFAR4 Q5NUL3 2/20 0.46
PPARG P37231 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
S1PR4 O95977 1/20 0.42
S1PR3 Q99500 1/20 0.42
S1PR5 Q9H228 1/20 0.42
MRGPRX4 Q96LA9 2/20 0.41
RXRA P19793 2/20 0.41
RXRB P28702 2/20 0.41
RXRG P48443 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13664800 0.95 S1PR1 (0.50) FFAR1S1PR1FFAR4PPARGPPARD
SCHEMBL13665586 0.90 FFAR1 (0.59) FFAR1S1PR1FFAR4PPARGPPARD
SCHEMBL13665224 0.86 FFAR1 (0.59) FFAR1S1PR1FFAR4S1PR3S1PR5
SCHEMBL86361 0.80 S1PR1 (0.72) S1PR1PPARGPPARDPPARAS1PR4
SCHEMBL13665427 0.79 RAB9A (0.47) S1PR1LMNAPOLBGAAS1PR4
Hydrochloric Acid SCHEMBL81203 0.79 S1PR1 (0.71) S1PR1PPARGPPARDPPARAS1PR4
SCHEMBL13665597 0.79 S1PR1 (0.55) FFAR1S1PR1PPARGPPARDPPARA
SCHEMBL13665327 0.78 S1PR1 (0.48) S1PR1PPARGPPARDPPARARXRA
SCHEMBL2950691 0.78 PDE4A (0.58) S1PR1PPARGPPARDPPARAPDE4A
SCHEMBL86411 0.77 S1PR1 (0.74) S1PR1PPARGPPARDPPARAPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009119858-A1 BENZENE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES 田辺三菱製薬株式会社 (JP) 2009-10-01 WO disclosed